LEVELS OF PROINFLAMMATORY CYTOKINES IL-17 AND IL-23 IN PATIENTS WITH ALZHEIMER’S DISEASE, MILD COGNITIVE IMPAIRMENT AND VASCULAR DEMENTIA

The aim: To research differences of interleukin (IL)-17 and IL-23 serum levels in patients with Alzheimer’s disease, vascular dementia mild cognitive impairment. Material methods: Serum IL-17 were measure by ELISA for 15 14 dementia, 30 impairment control individuals without Results: concentrations significantly higher disease (P=0.0023) than control, no significant differences(P=0.4154). Level was (P=0.0170) (P=0.0002), but it 12.5 time higher. In total concentration observed amnestic form (P=0.0436) (P=0.0019). Conclusions: level compared dementia. From detectable interleukins that may be early marker progression disease.